Paquimeningitis hipertrófica y alteraciones oftalmológicas: descripción de dos casos clínicos / Hypertrophic pachymeningitis and ophthalmological disturbances: description of two case reports

Caso clínico: Presentamos dos casos de paquimeningitis hipertrófica con alteraciones oftalmológicas asociadas. Uno de los pacientes presentó paquimeningitis hipertrófica presuntamente secundaria a neurosarcoidosis focal y paresia del sexto par. La segunda paciente presentó paquimeningitis hipertrófica crónica idiopática (tipo poco frecuente) difusa con alteraciones de la motilidad ocular y en la visión. Discusión: La paquimeningitis hipertrófica es una patología con un amplio espectro de etiologías y manifestaciones clínicas, que debe ser tenida en cuenta en el diagnóstico de alteraciones de la motilidad ocular

Case reports: We report two cases of hypertrophic pachymeningitis with ophthalmological disturbances. One patient suffered from hypertrophic pachymeningitis supposedly secondary to a focal neurosarcoidosis and had a sixth nerve paresis. The second patient suffered from a diffuse idiopathic hypertrophic chronic pachymeningitis (a rare form) and displayed disturbances in vision and ocular motility. Discussion: Hypertrophic pachymeningitis is a condition with a wide spectrum of etiologies and clinical manifestations, and needs to be considered as the cause in patients with alterations in ocular motility (Arch Soc Esp Oftalmol 2008; 83: 497-500)

[Hypertrophic pachymeningitis and ophthalmological disturbances: description of two case reports]. / Paquimeningitis hipertrófica y alteraciones oftalmológicas: descripción de dos casos clínicos.

CASE REPORTS: We report two cases of hypertrophic pachymeningitis with ophthalmological disturbances. One patient suffered from hypertrophic pachymeningitis supposedly secondary to a focal neurosarcoidosis and had a sixth nerve paresis. The second patient suffered from a diffuse idiopathic hypertrophic chronic pachymeningitis (a rare form) and displayed disturbances in vision and ocular motility. DISCUSSION: Hypertrophic pachymeningitis is a condition with a wide spectrum of etiologies and clinical manifestations, and needs to be considered as the cause in patients with alterations in ocular motility

Iris melanocytoma mimicking the Cogan-Reese syndrome with monocular pigment dissemination.

PURPOSE: To report a case of iris melanocytoma mimicking the Cogan-Reese syndrome. METHODS: A 37-year-old woman presented with pigmentary glaucoma in her left eye. There was diffuse pigmentary dispersion in the anterior segment, pedunculated pigmented nodules on the anterior iris surface, mild iris atrophy, and ectropion iridis. Neither intrinsic vasculature nor a sector cataract was found. The angle was open with marked trabecular pigmentation and no anterior synechiae. The intraocular pressure was 30 mmHg with maximum medical treatment and there was glaucomatous optic atrophy. The differential diagnosis included iris pigmented tumor and iridocorneal endothelial syndrome (Cogan-Reese syndrome). An iris biopsy was performed for diagnostic purposes. RESULTS: Histologic diagnosis after evaluation of the specimen was iris melanocytoma. CONCLUSIONS: This case presents signs considered quasi-pathognomonic of iridocorneal endothelial syndrome (Cogan-Reese syndrome): glaucoma, mild iris atrophy associated with pedunculated iris nodules, and ectropion iridis. Therefore, iris melanocytoma can present with features that mimic the Cogan-Reese syndrome.

[Juxtapapillary capillary hemangioma and central serous retinopathy: description of a case with spontaneous resolution]. / Hemangioma capilar yuxtapapilar y retinopatía central serosa: descripción de un caso con resolución espontánea.

CASE REPORT: A patient presented with a unilateral decrease of visual acuity and was found to have a juxtapapillary capillary hemangioma by ophthalmoscopy (confirmed by fluorescein angiography) and atrophy in the retinal pigmentary epithelium with leakage points suggesting bilateral central serous retinopathy. Spontaneous resolution of the hemangioma, as well as the central serous retinopathy, subsequently occurred. DISCUSSION: The decrease of visual acuity in a patient with a juxtapapillary capillary hemangioma has been associated with complications from the lesion itself, but an association of central serous retinopathy, as a possible predisposing factor, has not been previously described.

Hemangioma capilar yuxtapapilar y retinopatía central serosa: descripción de un caso con resolución espontánea / Juxtapapillary capillary hemangioma and central serous retinopathy: description of a case with spontaneous resolution

Caso clínico: Paciente con pérdida de agudezavisual unilateral. Funduscópicamente se observóuna masa compatible con hemangioma capilar yuxtapapilar(confirmada mediante angiofluoresceingrafía)y alteración del epitelio pigmentario y puntosde exudación en polo posterior compatibles conretinopatía central serosa bilateral.En la evolución se produjo regresión espontáneatanto del hemangioma como de la retinopatía centralserosa.Discusión: La pérdida de visión en un paciente conhemangioma capilar yuxtapapilar se ha relacionadocon complicaciones derivados del mismo, nohabiendo sido descrita la asociación con retinopatíacentral serosa, como factor contribuyente

Case report: A patient presented with a unilateral ;;decrease of visual acuity and was found to have a ;;juxtapapillary capillary hemangioma by ophthalmoscopy ;;(confirmed by fluorescein angiography) ;;and atrophy in the retinal pigmentary epithelium ;;with leakage points suggesting bilateral central ;;serous retinopathy. Spontaneous resolution of the ;;hemangioma, as well as the central serous retinopathy, ;;subsequently occurred. ;;Discussion: The decrease of visual acuity in a ;;patient with a juxtapapillary capillary hemangioma ;;has been associated with complications from the ;;lesion itself, but an association of central serous ;;retinopathy, as a possible predisposing factor, has ;;not been previously described

Variable-angle synchronous fluorescence spectrometry and rank annihilation methods for mixture resolution.

The potential of variable angle synchronous spectroscopy (VASS) for fluorescent mixtures resolution was assessed and compared with the rank annihilation method (RAM). For this purpose, a set of excitation-emission matrices from three standard cyclodextrin fluorescence-enhanced solutions of the pesticides aminocarb, carbendazim and coumatetralyl and a mixture of them was obtained. Careful selection of the spectral routes to be scanned provides analyte signals that are free of interferences. Application of the rank annihilation method to excitation-emission matrices (EEMs) obtained by conventional scanning spectrofluorimetry gives quantitative results that show poor precision and accuracy when compared to those of VASS. The recoveries from ternary mixtures by VASS are within 99-104% and by RAM within 84-130%.